This case study demonstrates how MedPharm stabilized a biologic formulation for topical nail delivery by identifying root causes of instability and optimizing excipient selection. Through targeted degradation studies and formulation optimization, MedPharm improved stability, reduced development risk, and enabled progression to IND-enabling studies.
Expanding Formulation Space to Strengthen Intellectual Property
This case study highlights how MedPharm expanded formulation space to strengthen intellectual property and increase commercial value for a topical drug product. By developing and evaluating multiple formulation types, including gels, creams, ointments, and foams, MedPharm enabled broader patent coverage while maintaining consistent product performance. The result was a more defensible IP strategy, reduced competitive risk, and enhanced long-term asset value.
Assessment of Wound Healing Treatments with Long Term Skin Culture Methods & a Novel Wounding Device
This scientific poster explores advanced methods for assessing wound healing using long-term human skin culture models. By combining a novel wounding device with MedPharm’s Skin-Life Extension Preparation (SLEP) and high-throughput pharmacodynamic (HTPD) system, the study demonstrates improved consistency, extended culture duration, and more informative evaluation of inflammation, proliferation, and tissue remodeling in wound healing research.
Robustness of Ex Vivo, Human Skin as a Model of General Inflammation
This scientific poster explores ex vivo human skin as a model of general inflammation, highlighting its use for evaluating inflammatory responses across Th1, Th2, Th17, and LPS pathways. The data demonstrates how human skin models can support pathway differentiation, inhibitor assessment, and more predictive preclinical decision-making in inflammatory drug development.
Use of Reconstructed Tissue and 3D Printed CT-Based Nasal Casts for the Assessment of Nasal Delivery
This scientific poster explores advanced in vitro models for nasal drug delivery, including reconstructed nasal epithelium and CT-based 3D printed nasal casts (MedCast®). These approaches enable more predictive assessment of drug permeation, penetration, and regional distribution compared to traditional methods, supporting improved formulation selection and reducing risk in drug development.
Videos & Webinars – Test 01
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Technical Resources – Test 01
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Scientific Publications – Test 01
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Case Studies & Program Insights – Test 01
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MedPharm’s Center for Skin Biology: The Standard of Quality
MedPharm’s Center for Skin Biology (CSB) provides scientifically rigorous, end-to-end support for substantiating cosmetic and personal care claims. With over 25 years of skin biology expertise, proprietary human skin models, and integrated preclinical and clinical capabilities, CSB generates reliable, performance-based data to support product claims and differentiate brands in a competitive market.